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To test whether plasma purine and monoamine metabolite concentrations were correlated in SZ, we studied previously published measurements (Yao et al., 2010a, b) of six purine metabolites (Hx, Xan, Xant, G, Gr, UA) for which concomitant measurements of 14 monoamine metabolites, tryptophan (TRP), serotonin (5-hydroxytryptamine, 5-HT), 5-hydroxyindoleacetic acid (5-HIAA), tryptamine (TRPA), melatonin (MEL), kynurenine (KYN), 3-hydroxykynurenine (3-OHKY), tryptophol (TPOL), tyrosine (TYR), L-3,4-dihydroxyphenylalanine (L-DOPA), Normetanephrine (NMET), homovanillic acid (HVA), 3-methoxy-4-hydroxyphenylglycol (MHPG), and vanillylmandelic acid (VMA), were also available from HC ( n = 30) and FENNS-BL ( n = 25) and FENNS-4w ( n = 25)

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Other possible side effects of a glutathione push include headache, nausea, and diarrhea

Conclusion This clinical trial provides robust evidence supporting the benefits of long-term GSH supplementation in improving oxidative stress and glycemic control in T2DM patients