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Description

How are GLP-1 agonists different from other diabetes medications like insulin

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Agonist-induced GLP-1R phosphorylation is mediated by GPCR kinases (GRKs) (4) and occurs predominantly on serine residues within the receptors intracellular C-terminal tail, with three serine (Ser) doublets previously identified as GLP-1R phospho-sites in positions 441/442, 444/445, and 451/452 (5) of the receptor

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