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GLP-1 agonist users may continue at maintenance doses long-term under medical supervision

Instead, it may support a broader body-composition plan by influencing: growth hormone signaling recovery lean mass preservation sleep quality in some protocols exercise response metabolic wellness Because lean mass is important during weight loss, peptides that support recovery and body composition may be useful in selected patients

Semaglutide works best when combined with other lifestyle efforts to support weight loss

For example, individuals with conditions like type 2 diabetes, hypertension, cardiovascular disease, or obstructive sleep apnea may benefit from intervention even if their BMI is below the standard threshold