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Murali 1,2 , (1)University of Iowa Hospitals and Clinics, (2)Orlando Health Background: Alpha-1antitrypsin (A1AT) Pi*MZ has been shown to increase the risk of liver related outcomes in patients with obesity and nonalcoholic fatty liver disease (NAFLD)

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Youdens index in conjunction with receiver operating characteristics (ROC) analysis was used to determine the best cut-off value of prognostic scores in predicting ALF and in-hospital death and area under ROC (AUROC) curves were compared using a paired data nonparametric ROC curve estimation