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In research terms, dose-related means that reported events may vary by the amount being studied and by the escalation approach used in the trial

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Empagliflozin was found to diminish the expression of TLR4 induced by high glucose in a human kidney proximal tubule cell line (159)

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reported that human islet amyloid polypeptide inhibited mitochondrial biogenesis, and treatment with exendin-4 partially restored it 10

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