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Modulating the expression or activity of ACSL4, LPCAT3, or ALOX directly alters cellular sensitivity to ferroptosis

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However, recent work supporting this hypothesis also demonstrated its role in the initiation and maintenance of seizures (Ksendzovsky et al., 2022)

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Decreased long-chain acylcarnitine content increases mitochondrial coupling efficiency and prevents ischemia-induced brain damage in rats

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