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According to the results of this study, the administration of LCAR to rats treated with radiation reversed the decrease in the levels of these genes compared to rats treated with radiation alone

The cGAS-STING pathway was initially defined as a cytoplasmic dsDNA sensorproinflammatory response axis that triggers the production of type I interferons and a broad range of other cytokines [20]

An in vivo study on rats showed that the gut microbiotas diversity was reduced by OTA treatment

Research from the SURPASS and SURMOUNT clinical trial programs has consistently shown this dual mechanism translates into superior clinical outcomes across nearly every measured endpoint