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When administered, semaglutide increases feelings of satiety, reduces hunger, and slows gastric emptying, all of which promote lower calorie intake

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The clinical relevance of these findings to humans remains unknown, and there is no evidence that acute overdose in humans increases thyroid cancer risk

The FDA-approved alternatives 1.7 mg or Wegovy HD 7.2 mg give providers more flexibility to match dose to tolerance and weight goals