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LawlorKEKhanNMildenhallAGerlicMCrokerBADCruzAAet alRIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

Cells have developed a sophisticated antioxidant system to protect against these oxidative insults, consisting of enzymes that either convert superoxide radicals into hydrogen peroxide (H 2 O 2 , SOD1, and catalases) or H 2 O 2 into water and oxygen [peroxiredoxin (Prx) and glutathione peroxidase (GPx)

The copper center's accessibility to redox cycling enables GHK-Cu to modulate oxidative stress responses in tissues experiencing inflammation or ischemic conditions

Lastly, the anti-ageing effects of antioxidants like Glutathione may also decrease the formation of wrinkles